99% Purity Vorinostat pharmaceutical intermediate CAS: 149647-78-9
Quick detail:
Name: Vorinostat
CAS: 149647-78-9
MF: C14H20N2O3
MW: 264.32
MP 161-162° C
Storage temp. -20° C Freezer
Chemical Properties White Crystalline Solid
Usage A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells.
Purity: 99%
Usage: API
Computed Properties
Molecular Weight: 264.3202 [g/mol]
Molecular Formula: C14H20N2O3
XLogP3: 1.9
H-Bond Donor: 3
H-Bond Acceptor: 3
Rotatable Bond Count: 8
Tautomer Count: 12
Exact Mass: 264.147393
MonoIsotopic Mass: 264.147393
Topological Polar Surface Area: 78.4
Heavy Atom Count: 19
Formal Charge: 0
Complexity: 276
Applications:
Suberoylanilide Hydroxamic Acid is a potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Suberoylanilide Hydroxamic Acid displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Suberoylanilide Hydroxamic Acid induces differentiation in uman breast cancer cells.
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Superiority:
We promise most of powders are in stock and chargeable samples are available. We have professional team special for package and shipment and staring on tracking code 24hours for customs pass guaranteed. High quality, reasonable price and fast and safety delivery is always our pursuit. It is certainly that warm after-sale service for you. Any of your question would be solved for the first as soon as possible.
COA
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Product Name |
Vorinostat (SAHA); Vorinostat(rINN);Suberoylanilide hydroxamic acid (SAHA);Suberanilohydroxamic acid; N-Hyrdroxy-N'-phenyloctanediamide;Zolinza;MK-0683;CCRIS 8456; Suberoylanilide Hydroxamic Acid |
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CAS No.: |
149647-78-9 |
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Synonyms |
Suberoylanilide hydroxamic acid; Suberanilohydroxamic acid; N-Hyrdroxy-N'-phenyloctanediamide; N1-hydroxy-N8-phenyl-octanediamide |
|
Molecular Formula |
C14H20N2O3 |
Molecular weight: |
264.32 |
|
Batch No.: |
131103 |
Mfg. Date |
2013.11.22 |
|
Quantity: |
100G |
Retest. Date |
2015.11.21 |
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Items |
Specifications |
Results |
|
Characteristics |
White to off-white crystal powder |
White crystal powder |
|
Melting Point: |
159°C~160.5°C |
159.3°C~160.2°C |
|
Related substances |
≤1.0% |
0.2% |
|
Single impurity |
≤0.5% |
Conforms |
|
Loss on drying |
≤1.0% |
0. 1% |
|
Residue on ignition |
≤0.1% |
0.01% |
|
Heavy metals |
≤10ppm |
Conforms |
|
Ethanol |
≤0.3% |
0.1% |
|
Purity (HPLC) |
≥99.0% |
99.% |
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