Hyaluronic Acid Cosmetic Grade Powder

Product name : Sodium hyaluronate
Latin name: hyaluronic acid
Specification : ≥98%
Active ingredent: Glucuronic acid
Appearance : white powder
CAS No.: 9067-32-7
Molecular Formula: (C14H20NO11)n
Molecular Weight: 1 800 000~2200 000
Glucuronic acid: Min 44%
Bacterial endotoxin: ≤0.05IU/mg
Background:  
Sodium hyaluronate is a straight chain macromolecular mucopolysaccharide composed Of repeat disaccharide units of glucuronic acid and N-acetylglucosamine. It widely consists in the extracellular space of human and animal tissue, vitreum, umbilical cord, skin joints synovia and cockscomb, etc.The commercial HA is commonly a sodium salt, called sodium hyaluronate, habitually called hyaluronic acid. Sodium hyaluronate is a new biological at home and abroad. Its molecular weight is from several ten thousand to several million. It's aqueous solution has outstanding moisture keeping ability, high viscoelasticity and lubricity. It is widely used in cosmetics, pharmacy and health and beauty food.
 
Hyaluronic acid may not be the newest or flashiest ingredient out there, but it's tried and true and seriously good for your skin. First off, don't let the word "acid" fool you. Hyaluronic acid isn't harsh or skin-stripping at all. In fact, it's the exact opposite - a powerful humectant (aka moisture-binding ingredient) that keeps skin plump and hydrated and, yes, young-looking.
Hyaluronic acid is a naturally occurring polysaccharide (carbohydrate) in the human body. It's present in large amounts in the spaces between skin cells, where it provides moisture, plumpness, firmness and suppleness to the skin.
Know how a baby's skin always looks so deliciously dewy and pillowy? It's because babies are born with a high level of hyaluronic acid, which keeps their skin plump and smooth. Unfortunately, the amount of hyaluronic acid in skin diminishes with age, most significantly after age 40.
While you're never going to get back that perfectly dewy baby-skin, it is possible to help restore the skin's hyaluronic acid content and give grown-up skin a younger, fresher, more supple look. One way to do it is through hyaluronic acid fillers, which a dermatologist or plastic surgeon injects directly into sunken or wrinkled areas to plump them up.
The other way to help plump up skin is to use a serum or moisturizer that contains hyaluronic acid. While it won't give you the dramatic, instantaneous results that a hyaluronic acid filler can, you will see benefits in the form of softer, smoother, more hydrated skin.
Applied topically, it increases hydration, improves elasticity and also reverses free radical damage, so it may have some benefit in protecting from UV damage. Bonus? Hyaluronic acid is one ingredient that works across the board. Every skin type, even oily, can benefit. Look for hyaluronic acid serums and apply one alone if you have oily skin or under moisturizer if you have dry skin.
Function:
Sodium hyaluronate is an important component of articular cartilage, where it is present as a coat around each cell (chondrocyte). When aggrecan monomers bind to hyaluronan in the presence of link protein, large highly negatively-charged aggregates form. These aggregates imbibe water and are responsible for the resilienceof cartilage (its resistance to compression). The molecular weight (size) of hyaluronan in cartilage decreases with age, but the amount increases.
Sodium hyaluronate is also a major component of skin, where it is involved in tissue repair. When skin is exposed to excessive UVB rays, it becomes inflamed (sunburn) and the cells in the dermis stop producing as much hyaluronan, and increase the rate of its degradation. Hyaluronan degradation products then accumulate in the skin after UV exposure.
While it is abundant in extracellular matrices, Sodium hyaluronate also contributes to tissue hydrodynamics, movement and proliferation of cells, and participates in a number of cell surface receptor interactions, notably those including its primary receptors, CD44 and RHAMM. Upregulation of CD44 itself is widely accepted as a marker of cell activation in lymphocytes. Sodium hyaluronate's contribution to tumor growth may be due to its interaction with CD44. Receptor CD44 participates in cell adhesion interactions required by tumor cells.
Although Sodium hyaluronate binds to receptor CD44, there is evidence hyaluronan degradation products transduce their inflammatory signal through toll-like receptor 2 (TLR2), TLR4 or both TLR2, and TLR4 in macrophagesand dendritic cells. TLR and hyaluronan play a role in innate immunity.
High concentrations of Sodium hyaluronate in the brains of young rats, and reduced concentrations in the brains of adult rats suggest hyaluronan plays an important role in brain development.
 
Sodium hyaluronate supplyment specifications
1. Food Grade
2. Cosmetic Grade
3. Eyedrops Grade(Pharm Grade)
4.Injection Grade(Pharm Grade)
 
Food grade Hyaluronic acid:

Test Items	Standard	Results
Appearance	White powder	Conformed
Hyaluronic Acid	≥95%	95.2%
Molecular weight	≥(0.8-1.5)X 106	0.85 X 106
Glucuronic acid	≥40%	43.57%
PH	5.5-7.5	6.8
Loss on drying	≤10%	9.1%
Nitrogen	3.0-4.0%	3.5%
Heavy metal	≤20ppm	Conformed
Arsenic	≤2ppm	Conformed
Heat remaining strong	≤20%	≤17.7%
Bacterial counts	≤100cfu/g	Conformed
Mold and Yeast	≤100cfu/g	Conformed
Staphylococcus aureus	Can not be checkout	Conformed
Chlorop seu domonas	Can not be checkout	Conformed

 
Packaging & Shipping
 
1. 25kg carton drum (32cm*58cm)or 1kg foil bag (10cm*15cm) or by request of clients.
2. 24/7 online service for your inquiries.
3. Free sample.
4. worldwide fastest delivery as soon as you pay.