99%High Quality Pharmaceutical Intermediates Levamisole Hydrochloride CAS: 16595-80-5

Pharmaceutical intermediates Levamisole hydrochloride CAS: 16595-80-5

Levamisole hydrochloride CAS: 16595-80-5

Product Description
Levamisole hydrochloride
CAS: 16595-80-5
MF: C11H13ClN2S
MW: 240.75
EINECS: 240-654-6
MP: 266-267 ° C(lit. )
Assay: 99%
Package: 25kg/cardboard
Usage: Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); Immunomodulator.
Appearance: White to almost white crystalline powder
as an anthelmintic for the treatment of
Usage: Levamisole is also a good alternative in cases of benzimidazole resistance. Levamisole Hydrochloride (Levamisole HCl), is an anthelmintic (animals roundworm, hookworm, etc.) agent commonly used in large livestock such as cattle, pigs and sheep.
It can selectively inhibit succinate dehydrogenase in parasite's muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite's muscle metabolism lacks of oxygen and leads to decreasing of energy.


Chemical Properties White to almost white crystalline powder
Usage Biological response modifier with anthelmintic activity. Anthelmintic (nematodes); immunomodulator.
Usage antifungal

Usage: Levamisole is also a good alternative in cases of benzimidazole resistance. Levamisole Hydrochloride (Levamisole HCl), is an anthelmintic (animals roundworm, hookworm, etc.) agent commonly used in large livestock such as cattle, pigs and sheep.
It can selectively inhibit succinate dehydrogenase in parasite's muscle so as to stop the reduction of succinic acid from fumaric acid. Therefore the parasite's muscle metabolism lacks of oxygen and leads to decreasing of energy.

2.  Description:

This product can be used as pharmaceutical raw materials, as an anthelmintic for the treatment of animals roundworm, hookworm, etc.

3.  Applications:

This for the tetramisole sinistral body that can selectively inhibit insect body muscle of succinate dehydrogenase, fumaric acid cannot revert to succinic acid, which affect anaerobic metabolism of insect body muscles, reduce energy production.When the insect body contact with neuromuscular depolarization, muscle sustained contraction occurred paralysis;Quasi choline drug effect of insect body eduction.The active about tetramisole (racemic form) 1 ~ 2 times, but a lower side effects.In addition, the drug to the worm microtubule structure may have inhibitory effect.Levamisole and immune adjustment and immune stimulation.The roundworm, hookworm, pinworm and dung round nematode disease has good curative effect.Because this product single dose efficient is higher, so it is suitable for group therapy.The bancroft silk worm, Malay silk worm and dish tail silk worm worm and activity of microfilariae ethylamine lamictal is high, but the long-term curative effect is poorer

4.  Specification:
    

Product Name	Levamisole hydrochloride	CAS No.: 16595-80-5
Items	Standard	Results
Characters	A white or almost white crystalline powder.	A white crystalline powder.
Identification	Specific optical rotation	Qualified
	IR
	Gives reaction of chlorides
Related substances	Each of impurities A, B, C, D, E≤0.2%	A: 0.02%, B: 0.01%, C: 0.09%, D: 0.00%, E: 0.00%
	Any other impurity≤0.1%	0.01%
	Total impurities≤0.3%	0.10%
Loss on drying	≤0.5%	0.1%
Sulfated ash	≤0.1%	0.03%
Heavy metals	≤0.002%	<0.002%
Assay	98.5%~101.0%	100.1%
Storage	Should be protected from light	protected from light
CONCLUSION	The product complies to the standard of BP2011, EP7.0

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