Beta cyclodextrin is a kind of white crystalline powder from tapioca starch by effect of glucosyltransferase.
Its unique cavity structure is constructed by 7 dextroses connecting together via α -1.4 bonds.
Outer side of the cavity keeps strong hydrophilic characteristics; Then inner side of the cavity keeps hydrophobic characteristics. It can entrap many kinds of guest molecules into their internal, particularly to entrap oil form substance and form inclusion complexes.
Beta cyclodextrin is widely used in foods, cosmetics and pharmaceutical industries as stabilizer, emulsifier, flavoring agent. etc.
Pharmaceutical application for example:
1. Improve drugs sability
2. Reduce drugs irritation, toxicity side effect and cover odor
3. Enhance drugs solibility
4. Improve drugs utilization
|
Appearance |
White crystal powder, smelless, little sweet |
White crystal powder, smelles, little sweet |
|
Distinguish |
Positive |
Complied |
|
Assay(dry basis) |
98%~102% |
99.6% |
|
Cleanness and color of solution |
In conformity |
Complied |
|
PH |
5.0-8.0 |
5.84 |
|
Reducing sugar |
≤1% |
Complied |
|
Solvent residual |
≤0.388% |
0.021% |
|
Impurity absorbance |
In conformity |
Complied |
|
Specific rotation |
+159°-+164° |
+161° |
|
Loss on drying |
≤14% |
11.5% |
|
Heavy metal |
≤10ppm |
<10ppm |
|
Residue on ignition |
≤0.1% |
0.02 |
|
Chloride |
≤0.018% |
Complied |
|
The total number of germ |
≤1000cfu/g |
<1000 |
|
The total number of mould & yeast |
≤100cfu/g |
<100 |
|
E.Coli |
Negative |
Complied |
|
Conclusion |
Check up to CP2010, approved |
