Product Specifications
| Prod Model: |
114977-28-5 |
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
| Purity: |
99% |
| Mf: |
C43h53no14 |
| MW: |
807.88 |
| Appearance: |
White Powder |
| Melting Point: |
232°c |
| Package: |
5/10/25 Kg / Aluminum Bags |
| Solubility: |
Insoluble in Water; Soluble in Alcohol. |
| Storage: |
Store in a Well-Closed Container |
Product Description
Docetaxel
1. Quick Details:
Docetaxel (CAS Number:114977-28-5)
Docetaxel, an Anti-cancer drug is used for the treatment of breast, ovarian and non-small cell lung cancer. It acts by damaging the structures needed for the cell division and stops the growth of cancer cells. The effect of this medication depends upon the type and extent of the cancer.
Chemical formula: C43H53NO14
Synonyms: Benzenepropanoicacid, b-[[(1,1dimethylethoxy)carbonyl] amino]-ahydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a, 3, 4, 4a, 5, 6, 9, 10, 11 ,12, 12a, 12b-dodecahydro-4, 6, 11-trihydroxy-4a, 8, 13, 13-tetramethyl-5-oxo-7, 11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-ylester;winthrop;docetaxol; docetaxolum.
Molecular weight: 807.88
Melting Point:232°C
Assay :99%
Boiling Point: 900.5 °C at 760 mmHg
Flash Point: 498.4°C
Appearance : white or almost white crystalline powder
Package : 5/10/25 kg / aluminum bags
2. Product Description:
| Product Name | Docetaxel Powder |
| Appearance | White crystalline powder |
| Active Ingredient | Docetaxel |
| CAS No | 114977-28-5 |
| Molecular formula | C43H53NO14 |
| Molecular weight | 807.88 |
| Specification | 99% |
| Melting point | 232 ºC |
| Alpha | -36 º (c=0.74,EtOH) |
| Solubility | Insoluble in water; soluble in alcohol. |
| Product Source | Docetaxel is paclitaxel in the process of structural transformation of taxol from derivatives. |
| Ash | ≤3.0% |
| Total Plate Count | ≤1000cfu/g |
| Yeast&Mold | ≤100cfu/g |
| Pathogenic bacteria | Negative |
| Salmonella | Negative |
Function | 1.It is a clinically well established anti-mitotic chemotherapy medication (that is, it
interferes with cell division).
2.It is used mainly for the treatment of breast, ovarian, and non-small cell lung cancer.
3.It has an FDA approved claim for treatment of patients who have locally advanced, or
metastatic breast or non small-cell lung cancer who have undergone anthracycline based chemotherapy and failed to stop cancer progression or relapsed. An European
approval docetaxel for use in hormone-refractory prostate cancer.
4.It is considered better than doxorubicin, paclitaxel and fluorouracil as a cytotoxic
antimicrotubule. |
| Storage | Store in a well-closed container away from moisture |
| Shelf Life | 2 years if sealed and store away from direct sun light. |
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