Product Specifications
| Prod Model: |
443913-73-3 |
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
| Function: |
Disinfectant and Preservatives |
| Grade Standard: |
Medicine Grade |
Product Description
Vandetanib (ZD6474; ZACTIMA™ , AstraZeneca) is a once-daily, orally available agent with potential for use in a number of solid tumor types. Vandetanib targets key signaling pathways in cancer by inhibiting VEGFR-dependent tumor angiogenesis, and EGFR- and RET-dependent tumor cell proliferation and survival. Phase I studies showed vandetanib to be generally well tolerated at doses of ≤ 300 mg/day, with a pharmacokinetic profile that supports once-daily oral administration. Phase II evaluation of vandetanib in patients with advanced refractory NSCLC has demonstrated improvements in progression-free survival both as monotherapy (versus gefitinib) and in combination with docetaxel (versus docetaxel alone). These positive outcomes have LED to the initiation of Phase III trials of vandetanib in advanced NSCLC. Clinical development is also ongoing in other tumor types and encouraging evidence of antitumor activity has been reported in patients with metastatic hereditary medullary thyroid cancer.
Guangzhou eastbang Pharmaceutical Technology Co., Ltd. is founded in 2006, based on the chemical and pharmaceutical science and technology based on high-tech enterprises, the company is committed to the biomedical and related fields of biological and chemical science and technology within the new product development and production; Global pharmaceutical company to market demand oriented set of innovative drug research and development, industry and marketization of the Chinese medicine business into business ventures in technology.
Companies have a good organic synthesis laboratories, have a professional database (Scienfinder, Beilstein) and documentation access systems, to quickly access a variety of synthetic literature; With the Shanghai Institute of Organic Chemistry and Analysis of the Test Center has established a good cooperative relationship, provide us with analytical testing services; We have synthesized high-quality professional staff, to quickly formulate a good synthetic route.
The company's strategic positioning is based in Guangzhou, Looking to the future, in the field of raw materials and new drugs can make a difference. Services for human health!
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