99% Voriconazole CAS: 137234-62-9 pharmaceutical intermediate
QUICK DETAIL:
NAME: Voriconazole
CAS: 137234-62-9
MF: C16H14F3N5O
MW: 349.31
MP: 127-130° C
Storage temp.: Store at +4° C
Chemical Properties: Cyrstalline Solid
Usage: An antifungal. An Ergosterol Biosynthesis inhibitor
Purity: 99%
Usage: API
Computed Properties
Molecular Weight: 349.31047 [g/mol]
Molecular Formula: C16H14F3N5O
XLogP3-AA: 1.5
H-Bond Donor: 1
H-Bond Acceptor: 4
Rotatable Bond Count: 5
Tautomer Count: 3
Exact Mass: 349.115045
MonoIsotopic Mass: 349.115045
Topological Polar Surface Area: 76.7
Heavy Atom Count: 25
Formal Charge: 0
Complexity: 448
USAGE:
1. Voriconazole is a triazole antifungal medication, it can cure empirical antifungal therapy
2. Voriconazole has become the new standard of care in the treatment of invasive aspergillosis.
3. Voriconazole can used in the treat of esophageal candidiasis
4. Voriconazole has also been used to treat severe fungal corneal infection
ABOUT US:
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Price |
Negotiated |
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Packaging Details |
1kg/aluminium foil bag or as required |
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Delivery time |
7-15 working days |
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Payment Terms |
Western Union, MoneyGram, T/T .PayPal |
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Supply Ability: |
Mass stock |
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Items |
Specification |
Results |
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Appearance |
White to off-white powder |
White powder |
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Solubility |
Freely soluble in dichloromethane and acetone; soluble in methanol and trichloromethane; slightly soluble in water |
Complies |
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Identification |
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(1) IR |
Sample IR spectrum corresponds to that of the standards |
Complies |
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(2) HPLC |
The retention time of the major peak of the sample solution corresponds to that of the standard solution, as obtained in the assay |
Complies |
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Test |
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Triazole acetophenone: ≤0.12% |
Not detected |
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Ethyl fluropyrimidine: ≤0.12% |
0.10% |
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Voriconazole related compound A: ≤0.12% |
Not detected |
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Related substance |
(RR,SS)6- Chlorovoriconazole: ≤0.12% |
0.09% |
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6- Chlorovoriconazole: ≤0.12% |
0.09% |
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Any unspecified impurity: ≤0.1% |
0.08% |
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Total impurities:≤0.5% |
0.40% |
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Heavy Metal |
NMT 10ppm |
<10ppm |
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Residue on ignition |
NMT 0.1% |
0.06% |
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Enantiomeric purity |
Voriconazole related compound B: ≤0.12% |
Not detected |
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Loss on Drying |
NMT 0.5% |
0.04% |
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Trichloromethane |
NMT 60ppm |
Not detected |
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Dichloromethane |
NMT 600ppm |
Not detected |
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Methanol |
NMT 3000ppm |
Not detected |
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2-propanol |
NMT 5000ppm |
200ppm |
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Acetone |
NMT 5000ppm |
Not detected |
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Assay( on dried basis ) |
98.0%~102.0% |
99.% |
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Conclusion |
Thse product complies with USP's pending Monographs Guideline |
Hongkong Yuancheng Saichuang Technology Co., Ltd, a leading manufacturer and supplier of Anabolic Steroid Hormone Powders, Pharmaceutical raw materials, Pharmaceutical Intermediates, Chemical raw materials, Food additives and Flavor & Fragrance in Hongkong. It was new company of Yuancheng Group, Hongkong, as the political, economic and cultural center as well as a regional commercial trade center, its unique geographical and cultural conditions are favorable for domestic and foreign trade.
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