Product Specifications
| Prod Model: |
Pharmacopoeial grade |
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
| Product Name: |
Dsip |
| CAS No.: |
62568-57-4 |
| Molecular Formula: |
C35h48n10o15 |
| Molecular Weight: |
848.81 |
| Purity: |
99%+ |
| Brand: |
Biocar |
| Origion: |
Hubei,China |
Product Description
Details
Delta sleep-inducing peptide, abbreviated DSIP, is a neuropeptide that when infused into the mesodiencephalic ventricle of recipient rabbits induces spindle and delta EEG activity and reduced motor activities.
Delta sleep-inducing peptide was first discovered in 1974 by the Swiss Schoenenberger-Monnier group who isolated it from the cerebral venous blood of rabbits in an induced state of sleep. It was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, but studies on the subject have been contradictory.
DSIP is an amphiphilic peptide of molecular weight 850 daltons with the amino acid motif:
N-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-C
It has been found in both free and bound forms in the hypothalamus, limbic system and pituitary as well as various peripheral organs, tissues and body fluids. In the pituitary it co-localises with many peptide and non-peptide mediators such as corticotropin-like intermediate peptide (CLIP), adrenocorticotrophic hormone (ACTH), melanocyte-stimulating hormone (MSH), thyroid-stimulating hormone (TSH) and melanin concentrating hormone (MCH). It is abundant in the gut secretory cells and in the pancreas where it co-localises with glucagon.
In the brain its action may be mediated by NMDA receptors. In another study Delta sleep-inducing peptide stimulated Acetyltransferase activity through α1 receptors in rats.It is unknown where DSIP is synthesized.
Application and Fuction:
Roles in endocrine regulation
Decreases basal corticotropin level and blocks its release
Stimulates release of luteinizing hormone (LH)
Stimulates release of somatoliberin and somatotrophin secretion and inhibits somatostatin secretion.
Roles in physiological processes
Can act as a stress limiting factor.
May have a direct or indirect effect on body temperature and alleviating hypothermia.
Can normalize blood pressure and myocardial contraction.
It has been shown to enhance the efficiency of oxidative phosphorylation in rat mitochondria in vitro, suggesting it may have antioxidant effects.
There is also conflicting evidence as to its involvement in sleep patterns. Some studies suggest a link between DSIP and slow-wave sleep (SWS) promotion and suppression of paradoxical sleep, (PS)while some studies show no correlation.Stronger effects on sleep have been noted for the synthesized analogues of DSIP.
It may have an impact on human lens epithelial cell function via the MAPK pathway, which is involved in cell proliferation, differentiation, motility, survival, and apoptosis.
For the product, we offer as follow
| Minimum Order Quantity | 100 g |
| Price | Negotiable |
| Lead Time | Within 24hours upon receipt of payment |
| Deliver Time | About 4-5 days |
| Package Details | Aluminum Foil Bags or Fiber Drum |
| Trade Term | CIF/CFR/FOB |
| Payment Terms | T/T L/C West Union |
Our advantages
1.High quality and competetive price
1)For DSIP exported we can offer COA Certificate and official Invoice.
2)We are manufacturer with own lab and factory, can provide high quality products with factory price.
3)Products purity is test by our quality department strictly before sending, and you can also ask the third testing organization come and inspect, such as (SGS/ CTI/ ITS), only after your confirmation will we send it out to you.
2.Fast and safe delivery:
1)Products can be sent out in 24 hours after payment. Tracking number available, fixed service person are 7x24h for you to contact.
2) Secure and discreet shipment. Various transportation methods for your choice, like DHL/UPS/TNT/FedEx/SF-express.
3)Customs pass and satisfied rate >99%.
4)For hot sale products we have stock in there for transferring.
3 We have clients throughout the world:
1) Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
2) Market feedback and goods feedback will be appreciated, meeting customers' requirement is our responsibility.
3) High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
Biocar is a leading manufacturer and supplier of Anabolic/Androgenic Steroid Hormone Powders, Pharmaceutical raw materials, Pharmaceutical Intermediates after decades years of experience.
From Wuhan University, Wuhan Institute of Technology and huazhong university of science& technology, we set up a group of technical experts, optimize the steroid synthetic and green production process to ensure that Biocar production technology in a leading international Level. Biocar steroid products have certified by GMP and COS, sales network spread over the countries in Asia, Europe, North America, South America.
Wuhan Biocar Bio-Pharm Co., Ltd was founded in 2001, formerly known as Tongshan Pharmaceutical Factory Company, which is a national high-tech enterprises. In 2014, in the process of creating a National Industrial Base, the Board of Directors decided to move the headquarter to Wuhan Biomedical Park. At the same time, with the advantages of the park policy, we carry out production and research cooperation with Humanwell Healthcare Gruop Co., Ltd, officially changed its name to Biocar Bio-Pharm Co., Ltd.
Website: http://www.biocarpharm.com or http://www.biocarpharm.com
ADD: 858 East Lake High-tech Development Zone Wuhan Hubei China
