Product Specifications
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
Product Description
100mg, 200mg/tablet, BP, CP standard.
We offer this product with best quality and competitive price. For more details, please feel free to contact with us.
Aciclovir differs from previous nucleoside analogues in that it contains only a partial nucleoside structure: The sugar ring is replaced by an open-chain structure. It is selectively converted into acyclo-guanosine monophosphate (acyclo-GMP) by viral thymidine kinase, which is far more effective (3000 times) in phosphorylation than cellular thymidine kinase. Subsequently, the monophosphate form is further phosphorylated into the active triphosphate form, acyclo-guanosine triphosphate (acyclo-GTP), by cellular kinases. Acyclo-GTP is a very potent inhibitor of viral DNA polymerase; It has approximately 100 times greater affinity for viral than cellular polymerase. As a substrate, acyclo-GTP is incorporated into viral DNA, resulting in chain termination. It has also been shown that viral enzymes cannot remove acyclo-GTP from the chain, which results in inhibition of further activity of DNA polymerase. Acyclo-GTP is fairly rapidly metabolised within the cell, possibly by cellular phosphatases.
In sum, aciclovir can be considered a prodrug: It is administered in an inactive (or less active) form and is metabolised into a more active species after administration.
Zhejiang Medicines and Health Products Import &Export Co., Ltd. (herein after called ZMC) is a subsidiary of Zhejiang International Business Group Co., Ltd. In the team spirit of "Putting the people in the forefront, exerting efforts for rigorous advancement", ZMC has evolved from a former state-owned enterprise in 1999 into a shareholding company with modern corporate governance structure and has been listed ever since 1990 among the top 500 exporters of China for 13 consecutive years. Through incessant efforts over the years on the exploitation for new and high quality products that help better meet our customers' needs and strengthen the competitiveness, our export revenue in 2008 hit a record high of USD 415 millions.
We have established extensive and pleasant working ties with numerous manufacturers within China on a long-term basis and enjoyed a reliable marketing network in over 100 countries and regions in Asia, Europe, America, Africa and Oceania, thus earning us a good corporate image based on "honoring contract and faithful to our commitment", quality service, efficient governance and risk-control management.
To complemen t and standardize our business operation so as to satisfy the requirements of our business partners at home and abroad, we have ISO9001: 2000 quality system certified and obtained GSP Certificat e respectively since 2001 and 2003. Our products line have also been expanded to cover a wide variety from the early pharmaceutical raw materials and traditional Chinese medicines(TCM) to today's active pharmaceutical ingredients, medicines, pharmaceutical raw materials, industrial chemicals, botanicals & crude drugs, plant & animal extracts, food additives and health products, medical instruments and equipments, surgical dressings & disposables, mechanical and electrical products, light industrial products, textiles and garments, etc (for detailed information, please click in the FOR EXPORT column of the web page).
In recent years our special efforts have been made in the industrial investment in those fields closely connected with our export business so as to diversify our business and enhance our growth sustainability. Initial results reveal a successful and promising picture.
In the 21st century we will be guided by the scientific outlook on development and corporate culture of placing people at the core of our value and advance in a progressive manner to seek and create more values for our shareholders and bring more benefits to the society, especially in the medical and health care sector. All customers and clients, old and new, in and outside China are welcome to explore business and modes of various cooperation with us. Let's join our hands together to build a glorious future!
