Product Specifications
| Prod Model: |
98-92-0 |
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
| Product Name: |
Nicotinamide |
| CAS No.: |
98-92-0 |
| Assay: |
99% |
| Use: |
Vitamin Drugs |
| Export Markets: |
Global |
| Appearance: |
White Crystalline Powder |
Product Description
1. Quick Detail:
Nicotinamide
Synonyms: 3-PYRIDINECARBOXAMIDE;3-PYRIDINE CARBOXYLIC ACID AMIDE;3-PYRIDINECARBOXYLIC AMIDE;TIMTEC-BB SBB004283;NICETHAMIDUM;NIACINAMIDE;NICOTINIC ACID AMIDE;NICOTINAMIDE
CAS: 98-92-0
MF: C6H6N2O
MW: 122.12
EINECS: 202-713-4
Chemical Properties White crystalline powder
Usage Niacinamide USP is used as food additive, for multivitamin preparations and as intermediate for pharmaceuticals and cosmetics. WWW Link
Usage Niacinamide USP DC is used as food additive, for multivitamin preparations and as intermediate for pharmaceuticals WWW Link
Usage A water-soluble vitamin B, incorporated within nicotinamide cofactors such as NADH and NADPH.
Usage Vitamin B3; enzyme cofactor; anti-pellagra
General Description White powder.
Air & Water Reactions Water soluble.
2. Description:
Nicotinamide, (ni-k-t-n-md) also known as niacinamide and nicotinic amide, is the amide of nicotinic acid (vitamin B3 / niacin). Nicotinamide is a water-soluble vitamin and is part of the vitamin B group. Nicotinic acid, also known as niacin, is converted to nicotinamide in vivo, and, though the two are identical in their vitamin functions, nicotinamide does not have the same pharmacological and toxic effects of niacin, which occur incidental to niacin's conversion. Thus nicotinamide does not reduce cholesterol or cause flushing, although nicotinamide may be toxic to the liver at doses exceeding 3 g/day for adults. In cells, niacin is incorporated into nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucleotide phosphate (NADP), although the pathways for nicotinic acid amide and nicotinic acid are very similar. NAD+ and NADP+ are coenzymes in a wide variety of enzymatic oxidation-reduction reactions. It's produced by the aqueous aminolysis of 3-cyanopyridine (nicotinonitrile) and subsequent crystallization.
3. Applications:
Nicotinamide has demonstrated anti-inflammatory actions that may be of benefit to patients with inflammatory skin conditions. These conditions include acne vulgaris, and the compound can suppress antigen-induced, lymphocytic transformation and inhibit 3', 5'-cyclic-AMP phosphodiesterase. Nicotinamide has demonstrated the ability to block the inflammatory actions of iodides known to precipitate or exacerbate inflammatory acne.
NicAzel and Nicomide are the names of oral acne medications that include nicotinamide as their most predominant ingredient, based on this area of research. Nicotinamide is also found as part of a new adjunct supplement combination called, AzerizinTM. According to the makers of Azerizin, this adjunct is part of their prescription dietary supplement product, which they claim helps manage inflammatory skin conditions. Nicotinamide is also used topically as a 4% or 5% gel or cream - as effective as topical 1% clindamycin (8-week double-blind trial) performed at the New York University College of Medicine. Unlike topical Erythromycin or Clindamycin it does not precipitate bacterial resistance in treating inflammatory acne. Nicotinamide acne treatment is also available as Nicotinamide pads and cream.
Nicotinamide is also reported to be an effective skin whitener in topical application.
4. Specifications:
Items | Specification | Results |
| Characteristics | White crystalline powder | Pass |
| Assay | 99.0~101.0% | 99.7% |
| Heavy metals | ≤ 0.001 | < 0.001 |
| Related substances | Complies with the standard | pass |
| Sulphated ash | ≤ 0.02 | < 0.02 |
| Melting point | 234~240° C | 236.2~237.3° C |
| Loss on drying | < 1.0 | 0.40 |
| Chloride | ≤ 0.02 | 0.07
|
5. Our advantange
Packing
Professional packing with professional materials, and We'll give clients several Packing way to choose after you contact me through my email
Quality
Our company is a professional leading factory in China in pharmaceutical area, ach batch of steroid powders have to tested by our QC(quality control) department before they are allowed to sell.
Delivery
We can pack your powders within 48 hours after your payment, and corresponding picture of your powders' parcel will be sent to you.
Price
Best prices you're sure to be satisfied, the more you buy, the more competitive prices you get.
Payment
T/T in advance , WU or Money Gram
Wuhan Network Union E-commerce Co., Ltd is a Sale Department of Wuhan Yuancheng Group which is is a leading Chinese chemical supplier specializing in fine chemical, flavor, food additive, pharmaceutical intermediates.
The company invests large fund and brains to R&D department to research fine chemical, biochemical, pharmaceutical & its intermediates products that fit the demand of the market. High level research group, advanced apparatus and good scientific atmosphere ensure the quality of R&D. All the products in plant are the fruit of R&D department. Our products reach the advanced standard of domestic market, many of which reach the international standard.
The company capital asserts is above 100 million RMB. According to the GMP standard, the company has built 10000 m2 plant equipped the advanced equipment. The factory has a complete Q. A. & Q. C. System. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001. We have the authority of export and import biochemical, pharmaceutical & steroid hormone, pharmaceuical intermediates distributed by the company are sold both in the domestic and international market and highly recommended by our clients. In order to develop the market further, we are eager to cooperate with the manufactory and trading company around the globe to make a prosperous future.
We advocate a enterprise idea that"people first, lead in the development of science and technology, serving society", insist on taking the road that"link science and technology as a marriage ", base on high-standard, new technologe, high quality. We have one batch the high-tech talent who are the chemical industry manages, produces, develops, all kinds of professional and technical personnel's account for 30% of the total number of company, is devoted to research, development, production of the new high-tech product, introduce the products innovated constantly to the market. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001.
Our Staff will pursue high quality and perfect brand with untiring efforts, and inherit enterprising spirit on"candid, diligent, refinement, upwards", follow the enterprise management theory of"lives, services or soul of quality ", with the first-class products and high-quality service to meet market's demands.
