Product Specifications
| Prod Model: |
56-75-7 |
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
| Product Name: |
Chloroamphenicol |
| CAS No.: |
56-75-7 |
| Appearance: |
White to Grey-White Crystalline Powder |
| Export Markets: |
Global |
| Polciy: |
Re-Shipping Policy |
| Delivery: |
5-7 Working Days Door to Door |
| Assay: |
99% |
Product Description
1. Quick Detail:
Chloramphenicol
Synonyms: ,[theta-(theta,theta)]-;[R-(R*,R*)]-2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]ethanamide;2,2-dichloro-n-(2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl)-acetamid;2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-,[R-(R*,R*)]-Acetamide;2,2-dichloro-n-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-acetamid;Acetamide, 2,2-dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl);Acetamide, 2,2-dichloro-N-[2-hydroxy-1-(hydroxymethyl)-2-(4-nitrophenyl)ethyl]-, [R-(R*,R*)]-;Acetamide, 2,2-dichloro-N-[beta-hydroxy-alpha-(hydroxymethyl)-p-nitrophenethyl]-, D-threo-(-)-
CAS: 56-75-7
MF: C11H12Cl2N2O5
MW: 323.13
EINECS: 200-287-4
Chemical Properties White to grey-white crystalline powder
Usage antibacterial, antirickettsial, inhibits protein synthesis
Usage Chloramphenicol is unusual nitroaromatic metabolite produced by Streptomyces venezuelae, first published in 1947. Chloramphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Although restricted to ocular use, antibiotic resistance to other classes has refocused attention on this class. Chloramphenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Chloramphenicol has been extensively studied with over 35,000 literature citations.
Usage Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial
2. Description:
antibacterial, antirickettsial, inhibits protein synthesis
Usage Chloramphenicol is unusual nitroaromatic metabolite produced by Streptomyces venezuelae, first published in 1947. Chloramphenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Although restricted to ocular use, antibiotic resistance to other classes has refocused attention on this class. Chloramphenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Chloramphenicol has been extensively studied with over 35,000 literature citations.
Usage Broad spectrum antibiotic obtained from cultures of the soil bacterium Streptomyces venezuelae. It has a broad spectrum of activity against Gram-positive and gram-negative bacteria. Antibacterial; antirickettsial
3. Applications:
Chloramphenicol is on the World Health Organization's List of Essential Medicines, a list of the most important medications needed in a basic health system.
The most serious adverse effect associated with chloramphenicol treatment is bone marrow toxicity, which may occur in two distinct forms: Bone marrow suppression, which is a direct toxic effect of the drug and is usually reversible, and aplastic anemia, which is idiosyncratic (rare, unpredictable, and unrelated to dose) and generally fatal.
Because of its excellent blood-brain barrier penetration (far superior to any of the cephalosporins), chloramphenicol remains the first-choice treatment for staphylococcal brain abscesses. It is also useful in the treatment of brain abscesses due to mixed organisms or when the causative organism is not known.
Use of intravenous chloramphenicol has also been associated with gray baby syndrome, a phenomenon resulting from newborn infants' inability to metabolize chloramphenicol in the body. Other less serious reactions include fever, rashes, headache, and confusion. Prescription use is usually associated with monitoring of a patient's complete blood count. The drug should be discontinued upon appearance of reticulocytopenia, leukopenia, thrombocytopenia, anemia, or any other abnormal blood study findings attributable to chloramphenicol.
Although unpublished, recent research suggests chloramphenicol could also be applied to frogs to prevent their widespread destruction from fungal infections. It has recently been discovered to be a life-saving cure for chytridiomycosis in amphibians.
4. Specification:
APPEARANCE | white or yellow-white
crystalline powder | yellow-white crystalline powder |
| CRYSTALLINITY | meets the requirements | PASS |
| Identification | IR
UV
Reaction of chlorides. | Confirm |
| MELTING POINT | 149.0~153.0 °C | 150~151°C |
| SPECIFIC OPTICAL ROTATION | +18.5 ~ +20.5 | +19.6 |
| Acidity or alkalinity | Not more than 0.1ml | Confirm |
| CHLORIDE | ≤100PPM | PASS |
| LOSS ON DRYING | ≤0.5% | 0.0% |
| SULPHATED ASH | ≤0.1% | 0.04% |
| RELATED SUBSTANCES (TCL) | ≤0.5% | PASS |
| ASSAY (ON THE DRIED BASIS) | 98.0%-~102.0% | 99.6% |
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6. Our Service:
1. Fast Delivery: We can delivery within 24 hours upon receipt of your payment.
2. Quality can be promised. Hot sell to Worldwide.
3. Payment Terms: T/T Bank Transfer, Western Union and MoneyGram Available.
4. Free Sample available at any time.
5. Tracking your order at any time. Inform your order's further new situation at any time.
7. Our advantage
1. We have experience in exporting steroids, as you know, EU places much emphasis on them, and you must find a experienced partner who will assure you;
2. Quality: Our company is a professional leading factory in China in pharmaceutical area, We had stable customers and exported to Germany, Spain, UK, USA, Australia, Middle East, and any other countries. We can provide good references about our company. As for the quality of the products, we 're sure they can satisfy you well enough;
3. Package: Professional packing with professional materials
4. Delivery: We have products in stock, and we will deliver them soon when your PO arrived. Meanwhile we will give you the tracking number in order to make you know the exact location of the products. We will keep track of the product until they arrive you; We choose the best courier service for you, and with the delivery around 5-7 working days.
5. Service: Best Service with after-sales service and consultation
Wuhan Network Union E-commerce Co., Ltd is a Sale Department of Wuhan Yuancheng Group which is is a leading Chinese chemical supplier specializing in fine chemical, flavor, food additive, pharmaceutical intermediates.
The company invests large fund and brains to R&D department to research fine chemical, biochemical, pharmaceutical & its intermediates products that fit the demand of the market. High level research group, advanced apparatus and good scientific atmosphere ensure the quality of R&D. All the products in plant are the fruit of R&D department. Our products reach the advanced standard of domestic market, many of which reach the international standard.
The company capital asserts is above 100 million RMB. According to the GMP standard, the company has built 10000 m2 plant equipped the advanced equipment. The factory has a complete Q. A. & Q. C. System. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001. We have the authority of export and import biochemical, pharmaceutical & steroid hormone, pharmaceuical intermediates distributed by the company are sold both in the domestic and international market and highly recommended by our clients. In order to develop the market further, we are eager to cooperate with the manufactory and trading company around the globe to make a prosperous future.
We advocate a enterprise idea that"people first, lead in the development of science and technology, serving society", insist on taking the road that"link science and technology as a marriage ", base on high-standard, new technologe, high quality. We have one batch the high-tech talent who are the chemical industry manages, produces, develops, all kinds of professional and technical personnel's account for 30% of the total number of company, is devoted to research, development, production of the new high-tech product, introduce the products innovated constantly to the market. We own several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and UV spectrophotometer to analyze and control the products. The company has gotten the approval of ISO9001.
Our Staff will pursue high quality and perfect brand with untiring efforts, and inherit enterprising spirit on"candid, diligent, refinement, upwards", follow the enterprise management theory of"lives, services or soul of quality ", with the first-class products and high-quality service to meet market's demands.
