Hydroxypropyl-Beta-Cyclodextrin to Improve Stability, Bioavailability and Efficacy of Pharmaceuticals
Product Specifications
| Prod Model: |
Hydroxypropyl-beta-cyclodextrin |
| Markets: |
North America,South America,Eastern Europe,Southeast Asia,Africa,Oceania,Mid East,Eastern Asia,Western Europe |
| Uses: |
Improve Stability, Bioavailability and Efficacy of |
Product Description
| Synonym(s) | HP-β-CD |
| Catalog number | rsc001 |
| CAS Registry number | 128446-35-5 |
| MDL number: | C42(H)70-nO35(C3H7)n |
| EINECS number: | 2354.64614 |
| Molecular Formula | White powder |
| Formula Weight | ≥98.0% |
| Specification | mp 278°C(dec.) |
| Hazard Symbol | 25kg/drum |
Characteristics and usage:Introduction of Hydroxypropyl (s) into the molecular of beta-Cyclodextrin hydrate breaks inner annularhydrogen bond and thus it increases the water solubility of beta-Cyclodextrin hydrate without breaking its molecular cavity.In food and spice industry, HP-β-CD can increase stability and shelf-life of nutrient molecule, can cover or rectify unpleasant smell or taste of nutrient molecule. HP-β-CD has good water solubility, if the degree of substitution (DS) is greater than 4, it will be miscible with water, 50% ethanol and methanol water solution.In cosmetic industry, it acts as stabilizer, emulsifier, and odor remover. It can reduce the irritation to skin mucosa tissue cause by organic molecule in the cosmetics.In pharmaceutical industry, because of its low surface activity and hemolytic activity, it is an ideal solubilizer for injection or pharmaceutical excipient. It can improve water solubility of pharmaceuticals that disinclined to dissolve in water. It can improve stability, bioavailability and efficacy of pharmaceuticals. It can also adjust or control release rate of pharmaceuticals to reduce their side effects. It can be used in oral drugs, injections, mucosal drug delivery system (including nasal mucosa, the rectum, the cornea), transdermal drug delivery system, vehicle for lipophilic targeting drugs, also as protective agent and stabilizer for protein products.| Appearance | White powder |
Solubility in Water(25ºC,g/100ml) | ≥75 |
| (%)Loss on drying | ≤5 |
| (%)Ignited Residue | ≤0.5 |
| β-(%)Residual β-CD | ≤1 |
| Heavy Metals(ppm) | ≤10 |
| (%)Propylene Glycol | ≤1 |
Residual Propylene Oxide(ppm) | ≤ 1 |
| (MS) | 4-7 |
Established in 1991, Hebei Smart Chemicals Co. Ltd has expanded to a group enterprise with 8 chemical manufacturing plants and over 60 chemicals and pharmaceutical ingredients. The company's primary products are intermediate fine chemicals and additives for food/feed. For details of our products' specifications, please visit our website at: http://www.hebeismart.com/.
In 2003 due to expanding business growth, Hebei Smart Chemical Co. Ltd established a subsidiary in Shanghai.
The company's R&D Center has over 48 professional engineers, chemists and pH. Ds. On staff to provide our customers with the best expertise and sevice for special needs in synthetic fields.
Products from Hebei Smart Chemical Co. Ltd. Have been exported to over 30 countries in Asia, Europe, North America, South America and Africa. The total sales for the year 2014reached $ 150, 000, 000 (US).
With our high-quality products and highly-skilled professional team, we are confident in our ability to serve your business needs. If you are interested in our products, please contact us at your earliest convenience and a member of our service team will respond to you within 24 hours.
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